The kit is designed for detection of 16 germline mutations in the HRR genes and is used in screening for predisposition to breast, ovarian, prostate, pancreatic and stomach cancer.
✅The kit is compatible with almost all RT-PCR devices.
Detection Method | Real-Time PCR |
---|---|
Format | Qualitative Multiplex |
Sample |
Peripheral blood, Buccal scraping |
Detection of Mutations |
BRCA1: c.5266dupC, c.181T>G, c.5251C>T, c.4035delA, c.5161C>T, c.4675G>A, c.68_69del, c.3700_3704del, c.1961delA BRCA2: c.3749dupA, c.961_962insAA CHEK2: c.470T>C, c.1100delC, c.444+1G>A, c.893_897del PALB2: c.1592delT |
Number of Reactions | 48 Reactions |
Test Time | 90 Minutes |
Recommended Extraction Kit | DNA Tissue-100 |