The kit is designed for detection of 16 germline (blood) /Somatic (Tissue) mutations in the BRCA1 and BRCA2 genes and is used in diagnostics of hereditary forms of breast, ovarian, pancreatic and stomach cancer to determine an effective treatment strategy.
✅The kit is compatible with almost all RT-PCR devices.
Detection Method | Real-Time PCR (Melting Curves) |
---|---|
Test Format | Qualitative Multiplex |
Sample |
Peripheral blood, buccal smear (Blood) Formalin-fixed, paraffin-embedded tissue (FFPE-blocks) (Tissue) |
Detection of Mutations |
BRCA1: c.5266dupC, c.181T>G, c.5251C>T, c.5161C>T, c.4035delA, c.1961delA, c.4675G>A, c.68_69del, c.3700_3704del, c.4689C>G, c.3756_3759del BRCA2: c.3749dupA, c.961_962insAA, c.2897_2898del, c.8754+1G>A, 6174delT |
Number of Reactions | 48 Reactions |
Test Time | 90 Minutes |
Recommended Extraction Kit | DNA Tissue-100 / NK-Exra-M |